Eczema Cream

Say good-bye to dry, irritated skin!

Baby Eczema Cream

Soft on baby skin, but tough on irritations!

Psoriasis Cream

Say good-bye to dry, scaly skin!

100% NATURAL ECZEMA & PSORIASIS CREAM

Orellis is made with only the best organic ingredients proven to effectively treat skins conditions such as eczema and psoriasis.

Calendula

Calendula officinalis is also known as pot marigold and it grows in Mediterranean countries. Calendula has been used traditionally in European folk medicine to treat various inflammatory conditions like ulcers. Traditional folk medicine systems use Calendula due to the reported anti-pyretic, anti-inflammatory, anti-tumour and anti-microbial properties of Calendula flowers. The flowers were also used during the American civil war to treat wounds and as a remedy for different viral infections such as measles and smallpox. Currently, Calendula is used topically as alternative and complementary medicine in Europe to treat burns, cuts, rashes and dermatitis. This herb has beautiful yellow flowers, which are used to prepare infusions, tinctures, liquid extracts, creams and ointments. There are many different chemicals that have therapeutic activity that are trapped inside the flowers. These compounds in the flowers can be extracted or made available using water or different alcohols based on the chemical structures of each compound. Therefore, these chemicals are able to therapeutically benefit the applied skin surface.

The anti-oxidants in Calendula flowers also reduce the levels of reactive oxygen species, which are produced during inflammation by immune cells and causes tissue damage. Calendula flowers also have wound healing properties since the phytoconstituents increase the level of collagen, which is important for wound healing and skin repair.

Hydrocotyle

Hydrocotyle umbellata is also known as “acariçoba” and it grows in tropical regions like South America and India. This plant has long leaves and numerous small white flowers. Hydrocotyle is used by communities in South America like Brazil, Argentina and Cuba to treat inflammatory conditions like ulcers, eczema, dermatitis, psoriasis. In South American and Indian folk medicine, preparations of Hydrocotyle leaves or roots are taken either orally or used in a bath to treat these inflammatory conditions.

The leaves and the subterraneous parts (i.e. roots) of the Hydrocotyle plant contain various compounds that have therapeutic activity. However, these compounds are not readily available. Therefore, the compounds with biological activity are extracted using different alcohols and water depending on the chemical structure of each compound.

The leaves contain flavonoids, saponins and triterpenes. The anti-oxidants in Hydrocotyle leaves reduce the levels of reactive oxygen species produced by immune cells that cause tissue damage during inflammation. The leaves also contain hexadecanoic acid methyl ester, falcarinol and phytol, which reduces the levels of inflammatory proteins known as cytokines and inhibits the migration of immune cells like neutrophils. Also, the subterraneous parts of Hydrocotyle contain hibalactone. Research in a mouse model of inflammation and pain has shown that hibalactone has anti-inflammatory and anti-nociceptive (pain) properties. The mechanism of action of hibalactone is not completely understood but it is thought that hibalactone reduces the level of various inflammatory proteins and reduces the migration of immune cells to the site of inflammation.

Lappa Major

Arctium lappa or Lappa major is also known as burdock. It is an edible vegetable that is grown in most countries, especially in Asian countries like Japan. The seeds of Arctium lappa are used in traditional folk medicine due to its diuretic, anti-pyretic (fever) and detoxifying properties. Burdock is also used to treat gout, hypertension and other inflammatory diseases.

There are many different chemicals that have therapeutic activity that are trapped inside the roots and seeds of Arctium lappa. These compounds in the roots and seeds can be extracted or made available using water or different alcohols based on the chemical structures of each compound. Therefore, these chemicals are able to exert their beneficial biological activity when taken orally or on the applied skin surface.

The butanol extract from the roots of Arctium lappa inhibits a key inflammatory pathway known as the NFkB
pathway and reduces the level of inflammatory proteins known as cytokines associated with allergies and inflammation. Arctium lappa also reduces the level of B-hexosaminidase, which is an immune protein mediator that increases inflammatory proteins known as cytokines. Research has also shown that the roots of Lappa Major contains phenolic compounds which act as anti-oxidants by reducing the level of reactive species that can cause tissue damage during inflammation.

Propolis

Propolis is a dark resinous material that is produced by bees. The purpose of this natural material is to build, preserve and protect the bee hives. Due to its chemical composition and sticky consistency, propolis protects the hive from harsh environmental conditions like rain and high winds, pathogens that can cause infection such bacteria and fungi and predators like snakes and lizards. Bees produce propolis using materials surrounding the hive like plant pollen, plant secretions, wax, natural resins, as well as salivary secretions.

Propolis has been used for many centuries to treat various diseases and ailments. Greek and Roman doctors used propolis as a mouth disinfectant, anti-septic and to treat skin wounds. It was also used by Soviet doctors during World War II to treat tuberculosis. Currently, propolis is used topically as alternative and complementary medicine to treat wounds, burns, acne, and skin infections. In alternative and complementary medicine, propolis is also used to treat cold and flu symptoms and and also to prevent cavities and treat gingivitis.

Given that the purpose of propolis is to protect bee hives, it is no wonder that the compounds found in propolis have biological activity that can provide relief for various ailments. The compounds found in propolis with biological activity are extracted using different concentrations of different alcohols and water. Preparations of propolis are used to make toothpastes, mouthwashes, capsules, throat lozenges and creams.

The therapeutic activity of propolis is linked to the flavonoid, hydroxycinnamic acid and caffeic acid phenethyl ester (CAPE) content. Research has shown that CAPE inhibits the release of proteins responsible for inflammation and decreases the movement of immune cells to the site of inflammation. Also, CAPE activates the production of proteins known as cytokines with anti-inflammatory properties. The antioxidants
in propolis reduce the levels of reactive oxygen species produced by immune cells that cause tissue damage during inflammation. Research has shown that propolis has wound healing properties due to its ability to cause tissue remodelling and increase the wound healing rate.

Research has shown that the chemical constituents and levels of flavonoids is dependent on the environmental conditions including the location of the hive, the diversity of plants surrounding the hive, type of plant pollen used and the species of bee that produces the propolis. However, all propolis preparations have similar biological activities since this resinous material has the same purpose in nature, which is to protect the hive.



ORELLIS is developing a line of eczema and psoriasis lotions, soaps, shampoos, lip balms and much more!